DRAK2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76885

Novus Biologicals, part of Bio-Techne
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NBP1-76885
NBP1-76885SS
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all DRAK2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid peptide near the carboxy terminus of human DRAK2. The immunogen is located within the last 50 amino acids of DRAK2. Amino Acid Squence: SKRFRFDDSLPNPHE

Specificity

It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for DRAK2 Antibody - BSA Free

Western Blot: DRAK2 AntibodyBSA Free [NBP1-76885]

Western Blot: DRAK2 AntibodyBSA Free [NBP1-76885]

Western Blot: DRAK2 Antibody [NBP1-76885] - Analysis in Raji cell lysate with antibody at (A) 1 and B (2) ug/mL.

Immunocytochemistry/Immunofluorescence: DRAK2 Antibody [NBP1-76885] -

Immunocytochemistry/Immunofluorescence: DRAK2 Antibody [NBP1-76885] - Jurkat cells with DRAK2 antibody at 10 ug/mL.

Applications for DRAK2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10 ug/mL

Western Blot

0.5 ug/ml
Application Notes
An approximately 45 kDa band can be detected in Western Blot.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DRAK2

Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

Long Name

DAP Kinase-related Apoptosis-inducing Protein Kinase 2

Alternate Names

STK17B

Gene Symbol

STK17B

UniProt

AB011421 (Human)

Additional DRAK2 Products

Product Documents for DRAK2 Antibody - BSA Free

Product Datasheets

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Product Specific Notices for DRAK2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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