DRAM Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-88807

Novus Biologicals, part of Bio-Techne
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NBP2-88807
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all DRAM Antibodies »

Product Summary for DRAM Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of human DRAM. Peptide sequence: TMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVP The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for DRAM Antibody

Western Blot: DRAM Antibody [NBP2-88807]

Western Blot: DRAM Antibody [NBP2-88807]

Western Blot: DRAM Antibody [NBP2-88807] - WB Suggested Anti-DRAM Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: A549 cell lysateDRAM1 is supported by BioGPS gene expression data to be expressed in A549

Applications for DRAM Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DRAM

DRAM is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.

Alternate Names

Damage-regulated autophagy modulator, DNA damage-regulated autophagy modulator protein 1, DNA-damage regulated autophagy modulator 1, DRAMFLJ11259

Gene Symbol

DRAM1

Additional DRAM Products

Product Documents for DRAM Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DRAM Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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