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DRAM Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-92236

Novus Biologicals, part of Bio-Techne
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NBP2-92236-0.02ml
NBP2-92236-0.1ml

Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for DRAM Antibody - Azide and BSA Free

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRAM1 (NP_060840.2). GLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DRAM Antibody - Azide and BSA Free

Western Blot: DRAM AntibodyAzide and BSA Free [NBP2-92236]

Western Blot: DRAM AntibodyAzide and BSA Free [NBP2-92236]

Western Blot: DRAM Antibody [NBP2-92236] - Analysis of extracts of various cell lines, using DRAM at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 15s.

Applications for DRAM Antibody - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:200-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS with 50% glycerol, pH7.3.

Format

Azide and BSA Free

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DRAM

DRAM is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.; Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.

Alternate Names

Damage-regulated autophagy modulator, DNA damage-regulated autophagy modulator protein 1, DNA-damage regulated autophagy modulator 1, DRAMFLJ11259

Gene Symbol

DRAM1

Additional DRAM Products

Product Documents for DRAM Antibody - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DRAM Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov