Drebrin 1 Antibody (SR1092)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21733

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21733-100ul
NBP3-21733-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1092

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Drebrin 1 Antibodies »

Product Summary for Drebrin 1 Antibody (SR1092)

Immunogen

A synthesized peptide derived from human Drebrin 1 (Uniprot #: Q16643)

Specificity

Detects endogenous levels of total Drebrin 1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Drebrin 1 Antibody (SR1092)

Western Blot: Drebrin 1 Antibody (SR1092) [NBP3-21733] -

Western Blot: Drebrin 1 Antibody (SR1092) [NBP3-21733] - Western blot analysis using NBP3-21733 in (1) HeLa cell lysate; (2) PC-12 cell lysate.

Applications for Drebrin 1 Antibody (SR1092)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Drebrin 1

Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.

Alternate Names

D0S117E, DBN1, Drba, Drebrin A, Drebrin E, Drebrin E2

Gene Symbol

DBN1

Additional Drebrin 1 Products

Product Documents for Drebrin 1 Antibody (SR1092)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Drebrin 1 Antibody (SR1092)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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