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Drebrin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14933

Novus Biologicals, part of Bio-Techne
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NBP2-14933

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Drebrin 1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Drebrin 1. The exact sequence is proprietary.

Reactivity Notes

Bovine (85%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Drebrin 1 Antibody

Western Blot: Drebrin 1 Antibody [NBP2-14933]

Western Blot: Drebrin 1 Antibody [NBP2-14933]

Western Blot: Drebrin 1 Antibody [NBP2-14933] - Various tissue extracts (50 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Drebrin antibody diluted at 1:3000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-14933]

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-14933]

Immunohistochemistry-Paraffin: Drebrin 1 Antibody [NBP2-14933] - Paraffin-embedded rat hind brain. Drebrin antibody dilution: 1:500.
Western Blot: Drebrin 1 Antibody [NBP2-14933]

Western Blot: Drebrin 1 Antibody [NBP2-14933]

Western Blot: Drebrin Antibody [NBP2-14933] - Sample (30 ug of whole cell lysate) A: IMR32 7.5% SDS PAGE; antibody diluted at 1:10000.

Applications for Drebrin 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Drebrin 1

The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]

Alternate Names

D0S117E, DBN1, Drba, Drebrin A, Drebrin E, Drebrin E2

Gene Symbol

DBN1

Additional Drebrin 1 Products

Product Documents for Drebrin 1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Drebrin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.