DRP1 Antibody (4E11B11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-23489

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Predicted:

Bovine (90%), Chinese Hamster (97%), Mouse (94%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 4E11B11

Concentration

1.0 mg/ml

View all DRP1 Antibodies »

Product Specifications

Immunogen

Partial recombinant human DRP1 (between residues 100-250) expressed in E. coli.

Reactivity Notes

Use in Rat reported in scientific literature (PMID:32693013).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for DRP1 Antibody (4E11B11)

Western Blot: DRP1 Antibody (4E11B11) [NBP2-23489]

Western Blot: DRP1 Antibody (4E11B11) [NBP2-23489]

Western Blot: DRP1 Antibody (4E11B11) [NBP2-23489] - Analysis using DRP1 mouse mAb in (1) A549 and (2) Jurkat cell lysates.
Immunohistochemistry: DRP1 Antibody (4E11B11) [NBP2-23489]

Immunohistochemistry: DRP1 Antibody (4E11B11) [NBP2-23489]

Immunohistochemistry: DRP1 Antibody (4E11B11) [NBP2-23489] - Analysis of paraffin-embedded human cerebellum tissues using DRP1 mouse mAb with DAB staining.
Western Blot: DRP1 Antibody (4E11B11) [NBP2-23489]

Western Blot: DRP1 Antibody (4E11B11) [NBP2-23489]

Western Blot: DRP1 Antibody (4E11B11) [NBP2-23489] - Analysis using DRP1 mAb in human DRP1 recombinant protein. (Expected MW is 41.8 kDa)
View 2 more images

Applications for DRP1 Antibody (4E11B11)

Application
Recommended Usage

ELISA

1:10000

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

PBS, 0.5% protein stabilizer

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DRP1

A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.

Long Name

Dynamin-1-like protein

Alternate Names

DLP1, DNM1L, DVLP, Dymple, HdynIV

Entrez Gene IDs

10059 (Human)

Gene Symbol

DNM1L

UniProt

O00429 (Human)

Additional DRP1 Products

Product Documents for DRP1 Antibody (4E11B11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DRP1 Antibody (4E11B11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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