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Dtk/TYRO3 Antibody (OTI2C4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-48040

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # OTI2C4

Concentration

1.3 mg/ml

Product Summary for Dtk/TYRO3 Antibody (OTI2C4)

Immunogen

Full length human recombinant protein of human TYRO3 (NP_006284) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Specificity

This antibody is specific for Homo sapiens TYRO3 protein tyrosine kinase (TYRO3).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

96.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Dtk/TYRO3 Antibody (OTI2C4)

Western Blot: Dtk/TYRO3 Antibody (OTI2C4) [NBP1-48040]

Western Blot: Dtk/TYRO3 Antibody (OTI2C4) [NBP1-48040]

Western Blot: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TYRO3 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TYRO3.
Immunocytochemistry/ Immunofluorescence: Dtk/TYRO3 Antibody (OTI2C4) [NBP1-48040]

Immunocytochemistry/ Immunofluorescence: Dtk/TYRO3 Antibody (OTI2C4) [NBP1-48040]

Immunocytochemistry/Immunofluorescence: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY TYRO3.
Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (OTI2C4) [NBP1-48040]

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (OTI2C4) [NBP1-48040]

Immunohistochemistry-Paraffin: Dtk/TYRO3 Antibody (2C4) [NBP1-48040] - Staining of paraffin-embedded Human Ovary tissue using anti-TYRO3 mouse monoclonal antibody.

Applications for Dtk/TYRO3 Antibody (OTI2C4)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Immunohistochemistry-Paraffin

1:150

Immunoprecipitation

2ug/500ul

Western Blot

1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Tyro3/Dtk

May be involved in cell adhesion processes, particularly in the central nervous system.In case of filovirus infection, seems to function as a cell entry factor

Long Name

Tyrosine Protein Kinase Receptor TYRO3

Alternate Names

Brt, Dtk, Rse, Sky

Entrez Gene IDs

7301 (Human)

Gene Symbol

TYRO3

Additional Tyro3/Dtk Products

Product Documents for Dtk/TYRO3 Antibody (OTI2C4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dtk/TYRO3 Antibody (OTI2C4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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