DUSP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57949

Novus Biologicals, part of Bio-Techne
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NBP2-57949
NBP2-57949-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all DUSP2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GPTAVYFLRGGFDGFQGCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DUSP2 Antibody

Immunocytochemistry/ Immunofluorescence: DUSP2 Antibody [NBP2-57949]

Immunocytochemistry/ Immunofluorescence: DUSP2 Antibody [NBP2-57949]

Immunocytochemistry/Immunofluorescence: DUSP2 Antibody [NBP2-57949] - Staining of human cell line RT4 shows localization to nucleus & nuclear membrane. Antibody staining is shown in green.

Applications for DUSP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DUSP2

The protein encoded by the DUSP2 gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. (provided by RefSeq)

Alternate Names

dual specificity phosphatase 2, dual specificity protein phosphatase 2, PAC1, PAC-1

Gene Symbol

DUSP2

Additional DUSP2 Products

Product Documents for DUSP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for DUSP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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