DUSP22 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS6809

Novus Biologicals, part of Bio-Techne
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NLS6809
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Key Product Details

Species Reactivity

Validated:

Human, Bovine, Equine, Monkey, Primate, Rabbit

Predicted:

Mouse (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all DUSP22 Antibodies »

Product Specifications

Immunogen

Synthetic 17 aa peptide from near N-terminus of human DUSP22.

Epitope

near N-terminus of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Chicken (88%), Xenopus (82%).

Specificity

Human DUSP22. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DUSP15 (59%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for DUSP22 Antibody - BSA Free

Immunohistochemistry-Paraffin: DUSP22 Antibody - BSA Free [NLS6809]

Immunohistochemistry-Paraffin: DUSP22 Antibody - BSA Free [NLS6809]

Immunohistochemistry-Paraffin: MKS1 Antibody [NLS6809] - Analysis of anti-DUSP22 antibody with human kidney.

Applications for DUSP22 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

2 - 22 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: DUSP22

MKPX, also known as JSP-1 for Jnk Stimulatory Phosphatase-1, belongs to the LMW-DSP subfamily of phosphatases. MKPX has been shown to have the capacity to activate the c-Jun N-terminal kinase (Jnk) signaling pathway. The activation of Jnk has been implicated in a number of important physiological processes, including embryonic morphogenesis, cell survival and apoptosis. At least two mRNA transcripts have been reported. Jnk signaling has been linked to human disease conditions, such as tumor development, cardiac hypertrophy, ischemia/reperfusion injury, diabetes, hyperglycemia-induced apoptosis, and several neurodegenerative disorders.MKPX has been shown to be widely expressed with highest expression in heart, kidney, liver, lung, pancreas and placenta. ESTs have been isolated from a diverse set of human tissues libraries, especially blood and breast.Caution: The acronym MKPX also has been used to describe Dual Specificity Protein Phosphatase 7.

Alternate Names

dual specificity phosphatase 22, dual specificity protein phosphatase 22, EC 3.1.3.16, EC 3.1.3.48, FLJ35864, homolog of mouse dual specificity phosphatase LMW-DSP2, JKAP, JNK-stimulating phosphatase 1, JSP-1, JSP1JNK-stimulatory phosphatase-1, LMWDSP2, LMW-DSP2, Low molecular weight dual specificity phosphatase 2, Mitogen-activated protein kinase phosphatase x, MKP-x, MKPXMAP kinase phosphatase x, VHX

Entrez Gene IDs

54903 (Human)

Gene Symbol

DUSP22

Additional DUSP22 Products

Product Documents for DUSP22 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for DUSP22 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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