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Dynamin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16244

Novus Biologicals, part of Bio-Techne
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NBP2-16244

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Dynamin 2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Dynamin 2. The exact sequence is proprietary.

Localization

Cytoplasm; cytoskeleton; Cell junction; synapse; postsynaptic cell membrane; postsynaptic density

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

98 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Dynamin 2 Antibody

Western Blot: Dynamin 2 Antibody [NBP2-16244]

Western Blot: Dynamin 2 Antibody [NBP2-16244]

Western Blot: Dynamin 2 Antibody [NBP2-16244] - Rat tissue extract (50 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Dynamin 2 antibody diluted at 1:5000. HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: Dynamin 2 Antibody [NBP2-16244]

Immunocytochemistry/ Immunofluorescence: Dynamin 2 Antibody [NBP2-16244]

Immunocytochemistry/Immunofluorescence: Dynamin 2 Antibody [NBP2-16244] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.
Immunohistochemistry-Paraffin: Dynamin 2 Antibody [NBP2-16244]

Immunohistochemistry-Paraffin: Dynamin 2 Antibody [NBP2-16244]

Immunohistochemistry-Paraffin: Dynamin 2 Antibody [NBP2-16244] - Human breast carcinoma.

Applications for Dynamin 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Dynamin 2

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Four alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq]

Long Name

Dynamin-2

Alternate Names

DNM2, DYN2

Gene Symbol

DNM2

UniProt

Additional Dynamin 2 Products

Product Documents for Dynamin 2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Dynamin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.