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DYRK3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57912

Novus Biologicals, part of Bio-Techne
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NBP2-57912
NBP2-57912-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for DYRK3 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GVYDTFMMIDETKCPPCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTIQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DYRK3 Antibody

Immunocytochemistry/ Immunofluorescence: DYRK3 Antibody [NBP2-57912]

Immunocytochemistry/ Immunofluorescence: DYRK3 Antibody [NBP2-57912]

Immunocytochemistry/Immunofluorescence: DYRK3 Antibody [NBP2-57912] - Staining of human cell line SiHa shows localization to nucleoplasm & cytosol.

Applications for DYRK3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DYRK3

DYRK3, or dual specificity tyrosine-phosphorylation-regulated kinase 3, is a negative regulator of EPO-dependent erythropoiesis and may place an upper limit on red cell production during stress erythropoiesis. DYRK3 inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells, and may also act by regulating CREB/CRE signaling.

Long Name

Dual-specificity Tyrosine-[Y]-phosphorylation Regulated Kinase 3

Alternate Names

DYRK5, REDK, YAK3-2

Gene Symbol

DYRK3

Additional DYRK3 Products

Product Documents for DYRK3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for DYRK3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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