Dysbindin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16245

Novus Biologicals, part of Bio-Techne
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NBP2-16245
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Dysbindin Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Dysbindin. The exact sequence is proprietary.

Reactivity Notes

Pig (86%), Chicken (80%), Sheep (86%), Bovine (87%).

Localization

Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Dysbindin Antibody

Western Blot: Dysbindin Antibody [NBP2-16245]

Western Blot: Dysbindin Antibody [NBP2-16245]

Western Blot: Dysbindin Antibody [NBP2-16245] - Various tissue extracts (50 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Dysbindin antibody diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
Immunocytochemistry/ Immunofluorescence: Dysbindin Antibody [NBP2-16245]

Immunocytochemistry/ Immunofluorescence: Dysbindin Antibody [NBP2-16245]

Immunocytochemistry/Immunofluorescence: Dysbindin Antibody [NBP2-16245] - DIV9 rat E18 primary hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Dysbindin stained by Dysbindin antibody diluted at 1:500.Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody [11710] diluted at 1:500. Blue: Fluoroshield with DAPI.
Immunohistochemistry-Paraffin: Dysbindin Antibody [NBP2-16245]

Immunohistochemistry-Paraffin: Dysbindin Antibody [NBP2-16245]

Immunohistochemistry-Paraffin: Dysbindin Antibody [NBP2-16245] - Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using antibody at 1:500 dilution.
View 1 more images

Applications for Dysbindin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Dysbindin

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Alternate Names

DKFZp564K192, Dysbindin, Dysbindin-1, dystrobrevin binding protein 1, Dystrobrevin-binding protein 1, FLJ30031, Hermansky-Pudlak syndrome 7 protein, HPS7 protein, HPS7DBND, MGC20210, My031, SDY

Gene Symbol

DTNBP1

UniProt

Q96EV8 (Human)

Additional Dysbindin Products

Product Documents for Dysbindin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Dysbindin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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