Dystrobrevin beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38915

Novus Biologicals, part of Bio-Techne
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NBP2-38915
NBP2-38915-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Dystrobrevin beta Antibodies »

Product Summary for Dystrobrevin beta Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: MIAAYDSEGRGKLTVFSVKAMLATMCGGKMLDKLRYVFSQMSDSNGLMIFSKFDQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Dystrobrevin beta Antibody

Western Blot: Dystrobrevin beta Antibody [NBP2-38915]

Western Blot: Dystrobrevin beta Antibody [NBP2-38915]

Western Blot: Dystrobrevin beta Antibody [NBP2-38915] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue
Immunocytochemistry/ Immunofluorescence: Dystrobrevin beta Antibody [NBP2-38915]

Immunocytochemistry/ Immunofluorescence: Dystrobrevin beta Antibody [NBP2-38915]

Immunocytochemistry/Immunofluorescence: Dystrobrevin beta Antibody [NBP2-38915] - Immunofluorescent staining of human cell line HEK 293 shows localization to mitochondria.
Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody [NBP2-38915]

Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody [NBP2-38915]

Immunohistochemistry-Paraffin: Dystrobrevin beta Antibody [NBP2-38915] - Staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules.

Applications for Dystrobrevin beta Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dystrobrevin beta

Dystrobrevin beta encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternate Names

beta-dystrobrevin, DTN-B, dystrobrevin beta, dystrobrevin, beta, MGC17163, MGC57126

Gene Symbol

DTNB

UniProt

O60941 (Human)

Additional Dystrobrevin beta Products

Product Documents for Dystrobrevin beta Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Dystrobrevin beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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