Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all dystrophia myotonica containing WD repeat motif Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 609 and 659 of human dystrophia myotonica, WD repeat containing using the numbering given in entry NP_004934.1 (GeneID 1762).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for dystrophia myotonica containing WD repeat motif Antibody

Western Blot: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001]

Western Blot: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001]

Western Blot: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001] - Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibody used at for WB at 0.4 ug/ml.
Immunohistochemistry: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001]

Immunohistochemistry: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001]

Immunohistochemistry: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-DMWD used at a dilution of 1:1,000 ( 1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001]

Immunohistochemistry-Paraffin: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001]

Immunohistochemistry-Paraffin: dystrophia myotonica containing WD repeat motif Antibody [NB100-95001] - FFPE section of human seminoma. Affinity purified rabbit anti-DMWD 1:250. DAB staining using Immunohistochemistry Accessory Kit

Applications for dystrophia myotonica containing WD repeat motif Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: dystrophia myotonica containing WD repeat motif

The gene that codes for DMWD (dystrophia myotonica WD-repeat containing protein) is located in the myotonic dystrophy (DM1) gene cluster on 19q. Mutations in the DM1 region affect DMPK (myotonic dystrophy protein kinase), a myosin kinase expressed in skeletal muscle, and are the cause of myotonic dystrophy, a form of muscular dystrophy characterized by wasting of the muscles and myotonia. DMWD is expressed ubiquitously and is most abundant in the testes and brain. Studies concerning its abundance and sub-cellular localization in brain tissue suggest that it may have a role in some of the mental symptoms associated with myotonic dystrophy.

Alternate Names

D19S593E, DM9, DMRN9, DMR-N9, dystrophia myotonica WD repeat-containing protein, dystrophia myotonica, WD repeat containing, dystrophia myotonica-containing WD repeat motif, Dystrophia myotonica-containing WD repeat motif protein, gene59, Protein 59, Protein DMR-N9

Entrez Gene IDs

1762 (Human)

Gene Symbol

DMWD

UniProt

NP_004934.1 (Human)

Additional dystrophia myotonica containing WD repeat motif Products

Product Documents for dystrophia myotonica containing WD repeat motif Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for dystrophia myotonica containing WD repeat motif Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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