E-Cadherin Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-84588

Novus Biologicals, part of Bio-Techne
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NBP1-84588
NBP1-84588-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all E-Cadherin Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (80%)

Marker

Epithelial Cell Marker, Adherens Junctions Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for E-Cadherin Antibody - BSA Free

Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588]

Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588]

Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588] - Staining in human colon and testis tissues . Corresponding CDH1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588]

Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588]

Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588]

Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588]

Immunohistochemistry-Paraffin: E-Cadherin Antibody [NBP1-84588] - Staining of human colon shows moderate positivity in plasma membrane in glandular cells.
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Applications for E-Cadherin Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: E-Cadherin

E-cadherin, or epithelial cadherin, is an cell-cell adhesion glycoprotein important to cellular processes such as morphology, polarity, development, tissue integrity and migration. E cadherin's extracellular domain interacts with other E-cadherin protein on adjacent epithelial cells to establish adhesion between them. E cadherin has also been identified as a tumor and metastasis suppressor, and its mutations have been linked to various forms of cancer.

Alternate Names

Arc-1, CAD1, Cadherin-1, CD324, CDH1, Cell-CAM120/80, ECAD, ECadherin, L-CAM, Uvomorulin

Gene Symbol

CDH1

Additional E-Cadherin Products

Product Documents for E-Cadherin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for E-Cadherin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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