ECEL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17582

Novus Biologicals, part of Bio-Techne
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NBP3-17582-100ul
NBP3-17582-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ECEL1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADAVEQKAQEILQVEQQLANITVSEHDDLR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ECEL1 Antibody

Immunohistochemistry-Paraffin: ECEL1 Antibody [NBP3-17582]

Immunohistochemistry-Paraffin: ECEL1 Antibody [NBP3-17582]

Immunohistochemistry-Paraffin: ECEL1 Antibody [NBP3-17582] - Staining of human hypothalamus shows strong cytoplasmic positivity in neurons.

Applications for ECEL1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ECEL1

ECEL1 encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes. [provided by RefSeq]

Alternate Names

damage induced neuronal endopeptidase, DINE, EC 3.4.24, EC 3.4.24.-, EC 3.4.24.11, ECEX, endothelin converting enzyme-like 1, endothelin-converting enzyme-like 1, Xce protein, XCEX converting enzyme

Gene Symbol

ECEL1

Additional ECEL1 Products

Product Documents for ECEL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ECEL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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