ECSIT Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76594

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-76594
NBP1-76594-0.025mg
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all ECSIT Antibodies »

Product Specifications

Immunogen

Antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human ECSIT. The immunogen is located within amino acids 290 - 340 of ECSIT. Amino Acid Squence: PPEEREVEETPEEW

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ECSIT Antibody - BSA Free

Western Blot: ECSIT AntibodyBSA Free [NBP1-76594]

Western Blot: ECSIT AntibodyBSA Free [NBP1-76594]

Western Blot: ECSIT Antibody [NBP1-76594] - Human heart cell lysates with ECSIT antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
Immunohistochemistry-Paraffin: ECSIT Antibody - BSA Free [NBP1-76594]

Immunohistochemistry-Paraffin: ECSIT Antibody - BSA Free [NBP1-76594]

Immunohistochemistry-Paraffin: ECSIT Antibody [NBP1-76594] - Mouse heart cells with ECSIT antibody at 2 ug/ml.
ECSIT Antibody - BSA Free

Immunohistochemistry: ECSIT Antibody - BSA Free [NBP1-76594] -

Immunohistochemistry: ECSIT Antibody - BSA Free [NBP1-76594] - Immunohistochemistry of ECSIT in mouse heart cells with ECSIT antibody at 2 u/mL.
View 1 more images

Applications for ECSIT Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

2 ug/ml

Immunohistochemistry-Paraffin

2 ug/ml

Western Blot

0.5-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ECSIT

Activation of NF-kappaB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses. Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6. ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway. Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.

Alternate Names

ECSIT homolog (Drosophila), evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, likely ortholog of mouse signaling intermediate in Toll pathway evolutionarilyconserved, Protein SITPEC, signaling intermediate in Toll pathway evolutionarily conserved ortholog, SITPECsignaling intermediate in Toll pathway, evolutionarily conserved

Gene Symbol

ECSIT

UniProt

NP_057665 (Human)

Additional ECSIT Products

Product Documents for ECSIT Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ECSIT Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.