Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all EDA-A1/Ectodysplasin A1 Antibodies »

Product Specifications

Immunogen

EDA-A1 antibody was raised against an 19 amino acid peptide near the center of human EDA-A1. The immunogen is located within amino acids 130 - 180 of EDA-A1. Amino Acid Squence: PDEKPYSEEESRRVRRNKR

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Bovine: (89%)

Specificity

EDA-A1/Ectodysplasin A1 antibody is human, mouse and rat reactive. Multiple isoforms of EDA-A1/Ectodysplasin A1 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for EDA-A1/Ectodysplasin A1 Antibody - BSA Free

Western Blot: EDA-A1/Ectodysplasin A1 AntibodyBSA Free [NBP2-81908]

Western Blot: EDA-A1/Ectodysplasin A1 AntibodyBSA Free [NBP2-81908]

Western Blot: EDA-A1/Ectodysplasin A1 Antibody [NBP2-81908] - Analysis of EDA-A1/Ectodysplasin A1 in mouse kidney tissue lysate with EDA-A1/Ectodysplasin A1 antibody at 1 ug/ml in (A) the absence and (B) presence of blocking peptide.
Immunohistochemistry: EDA-A1/Ectodysplasin A1 Antibody - BSA Free [NBP2-81908]

Immunohistochemistry: EDA-A1/Ectodysplasin A1 Antibody - BSA Free [NBP2-81908]

Immunohistochemistry: EDA-A1/Ectodysplasin A1 Antibody [NBP2-81908] - Analysis of EDA-A1/Ectodysplasin A1 in mouse kidney tissue with EDA-A1/Ectodysplasin A1 antibody at 5 ug/ml.
EDA-A1/Ectodysplasin A1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: EDA-A1/Ectodysplasin A1 Antibody - BSA Free [NBP2-81908] -

Immunocytochemistry/ Immunofluorescence: EDA-A1/Ectodysplasin A1 Antibody - BSA Free [NBP2-81908] - Immunofluorescence of EDA-A1/Ectodysplasin A1 in mouse kidney tissue with EDA-A1/Ectodysplasin A1 antibody at 20 u/ml.

Applications for EDA-A1/Ectodysplasin A1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EDA-A1/Ectodysplasin A1

Ectodysplasin-A1 (EDA-A1) is a type II transmembrane protein belonging to the TNF superfamily. It is one of multiple isoforms encoded by the EDA gene. Human EDA-A1 is a 391 amino acid protein with a predicted molecular mass of 41 kDa. Mouse and rat EDA-A1 share 94% amino acid sequence identity with the human protein. EDA-A1 is expressed by keratinocytes, hair follicles, and sweat glands, where it can be localized to the cell surface or cleaved into a soluble form by Furin. EDA-A1 forms a homotrimeric protein that binds to EDAR and activates NF-kappa B signaling. Mutations in EDA are associated with a group of developmental disorders identified as ectodermal dysplasia type 1.

Alternate Names

EDAA1

Gene Symbol

EDA

Additional EDA-A1/Ectodysplasin A1 Products

Product Documents for EDA-A1/Ectodysplasin A1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EDA-A1/Ectodysplasin A1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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