EDA2R/TNFRSF27/XEDAR Antibody (3C1)

Novus Biologicals, part of Bio-Techne | Catalog # H00060401-M02

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 3C1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all EDA2R/TNFRSF27/XEDAR Antibodies »

Product Specifications

Immunogen

EDA2R (NP_068555, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQ

Specificity

EDA2R - ectodysplasin A2 receptor

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for EDA2R/TNFRSF27/XEDAR Antibody (3C1)

Western Blot: EDA2R/TNFRSF27/XEDAR Antibody (3C1) [H00060401-M02]

Western Blot: EDA2R/TNFRSF27/XEDAR Antibody (3C1) [H00060401-M02]

Western Blot: EDA2R/TNFRSF27/XEDAR Antibody (3C1) [H00060401-M02] - EDA2R monoclonal antibody (M02), clone 3C1. Analysis of EDA2R expression in Raw 264.7.
Sandwich ELISA: EDA2R/TNFRSF27/XEDAR Antibody (3C1) [H00060401-M02] - Detection limit for recombinant GST tagged EDA2R is approximately 1ng/ml as a capture antibody.

Applications for EDA2R/TNFRSF27/XEDAR Antibody (3C1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: EDA2R/TNFRSF27/XEDAR

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.

Long Name

Ectodysplasin A2 Receptor

Alternate Names

EDAA2R, TNFRSF27, XEDAR

Entrez Gene IDs

60401 (Human)

Gene Symbol

EDA2R

OMIM

300276 (Human)

UniProt

NP_068555

Additional EDA2R/TNFRSF27/XEDAR Products

Product Documents for EDA2R/TNFRSF27/XEDAR Antibody (3C1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for EDA2R/TNFRSF27/XEDAR Antibody (3C1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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