EDNRA/Endothelin R Type A Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS4067

Novus Biologicals, part of Bio-Techne
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NLS4067
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all EDNRA/Endothelin R Type A Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human EDNRA/Endothelin R Type A.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Monkey (89%), Sheep (89%), Bat (89%), Canine (83%), Bovine (83%), Equine (83%).

Localization

Membrane; multi pass membrane protein.

Specificity

Human EDNRA/Endothelin R Type A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for EDNRA/Endothelin R Type A Antibody - BSA Free

Immunohistochemistry-Paraffin: EDNRA/Endothelin R Type A Antibody - BSA Free [NLS4067]

Immunohistochemistry-Paraffin: EDNRA/Endothelin R Type A Antibody - BSA Free [NLS4067]

Immunohistochemistry-Paraffin: EDNRA/Endothelin R Type A Antibody [NLS4067] - Analysis of anti-Endothelin A Receptor antibody with human heart.

Applications for EDNRA/Endothelin R Type A Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

16 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: EDNRA/Endothelin R Type A

The ETA receptor is an Endothelin Receptor that mediates the effects of endothelin-1, a mitogen with potent contractile properties. In the human fetal olfactory epithelium cell line FNC-B4, the ETA receptor increases the secretion of gonadotropin-releasing hormone. Increased ETA concentration may be correlated with smooth muscle hypertrophy observed in patients suffering from bladder-outlet obstruction. ETA receptor has been reported in a variety of tissues including placenta, uterus, testis, heart, adrenal gland, lung, kidney, ovary, skin, liver, bladder, large blood vessels, cerebellum, neurons, and meningioma tumor cells. A splice variant has been identified in melanoma (Zhang et al., 1998). ESTs have been isolated from libraries from the above-mentioned tissues.

Long Name

Endothelin Receptor Type A

Alternate Names

EDNRA, ETAR, ETRA

Entrez Gene IDs

1909 (Human)

Gene Symbol

EDNRA

Additional EDNRA/Endothelin R Type A Products

Product Documents for EDNRA/Endothelin R Type A Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for EDNRA/Endothelin R Type A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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