EDNRA/Endothelin R Type A Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS4069

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NLS4069
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Monkey

Predicted:

Canine (94%), Equine (94%), Hamster (94%), Mouse (94%), Primate (100%), Rabbit (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all EDNRA/Endothelin R Type A Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from 3rd extracellular domain of human EDNRA/Endothelin R Type A.

Epitope

3rd extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Gibbon (94%), Sheep (89%), Bovine (89%), Bat (89%), Opossum (89%).

Localization

Membrane; multi pass membrane protein.

Specificity

Human EDNRA/Endothelin R Type A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except EDNRB (72%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for EDNRA/Endothelin R Type A Antibody - BSA Free

Immunohistochemistry-Paraffin: EDNRA/Endothelin R Type A Antibody - BSA Free [NLS4069]

Immunohistochemistry-Paraffin: EDNRA/Endothelin R Type A Antibody - BSA Free [NLS4069]

Immunohistochemistry-Paraffin: EDNRA/Endothelin R Type A Antibody [NLS4069] - Analysis of anti-Endothelin A Receptor antibody with human heart.

Applications for EDNRA/Endothelin R Type A Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

3 - 16 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: EDNRA/Endothelin R Type A

The ETA receptor is an Endothelin Receptor that mediates the effects of endothelin-1, a mitogen with potent contractile properties. In the human fetal olfactory epithelium cell line FNC-B4, the ETA receptor increases the secretion of gonadotropin-releasing hormone. Increased ETA concentration may be correlated with smooth muscle hypertrophy observed in patients suffering from bladder-outlet obstruction. ETA receptor has been reported in a variety of tissues including placenta, uterus, testis, heart, adrenal gland, lung, kidney, ovary, skin, liver, bladder, large blood vessels, cerebellum, neurons, and meningioma tumor cells. A splice variant has been identified in melanoma (Zhang et al., 1998). ESTs have been isolated from libraries from the above-mentioned tissues.

Long Name

Endothelin Receptor Type A

Alternate Names

EDNRA, ETAR, ETRA

Entrez Gene IDs

1909 (Human)

Gene Symbol

EDNRA

Additional EDNRA/Endothelin R Type A Products

Product Documents for EDNRA/Endothelin R Type A Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for EDNRA/Endothelin R Type A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.