Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all EFCAB4A Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A. The immunogen is located within amino acids 290 - 340 of EFCAB4A. Amino Acid Squence: ESEARGRQEQTQRDV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EFCAB4A Antibody - BSA Free

Western Blot: EFCAB4A AntibodyBSA Free [NBP1-76492]

Western Blot: EFCAB4A AntibodyBSA Free [NBP1-76492]

Western Blot: EFCAB4A Antibody [NBP1-76492] - human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 ug/mL.

Applications for EFCAB4A Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EFCAB4A

EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.

Alternate Names

Calcium release-activated calcium channel regulator 2B, CRAC channel regulator 2B, CRACR2B, EF-hand calcium binding domain 4A, EF-hand calcium-binding domain-containing protein 4A, FLJ46033, MGC45840, MGC88858

Gene Symbol

CRACR2B

UniProt

NP_775855 (Human)

Additional EFCAB4A Products

Product Documents for EFCAB4A Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EFCAB4A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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