EFCAB4B Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76493

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all EFCAB4B Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B. The immunogen is located within amino acids 640 - 690 of EFCAB4B. Amino Acid Squence: KLDNEKEREVPRGL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EFCAB4B Antibody - BSA Free

Western Blot: EFCAB4B AntibodyBSA Free [NBP1-76493]

Western Blot: EFCAB4B AntibodyBSA Free [NBP1-76493]

Western Blot: EFCAB4B Antibody [NBP1-76493] - mouse kidney tissue lysate with EFCAB4B antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: EFCAB4B Antibody - BSA Free [NBP1-76493]

Immunocytochemistry/ Immunofluorescence: EFCAB4B Antibody - BSA Free [NBP1-76493]

Immunocytochemistry/Immunofluorescence: EFCAB4B Antibody [NBP1-76493] - Immunofluorescence of EFCAB4B in human kidney tissue with EFCAB4B antibody at 20 ug/mL.
Immunohistochemistry: EFCAB4B Antibody - BSA Free [NBP1-76493]

Immunohistochemistry: EFCAB4B Antibody - BSA Free [NBP1-76493]

Immunohistochemistry: EFCAB4B Antibody [NBP1-76493] - Immunohistochemistry of EFCAB4B in human kidney tissue with EFCAB4B antibody at 10 ug/mL.
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Applications for EFCAB4B Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EFCAB4B

EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation.

Alternate Names

Calcium release-activated calcium channel regulator 2A, CRAC channel regulator 2A, CRACR2A, DKFZp686G13246, EF-hand calcium binding domain 4B, EF-hand calcium-binding domain-containing protein 4B, FLJ33046, FLJ33805, MGC4266

Gene Symbol

CRACR2A

UniProt

NP_116069 (Human)

Additional EFCAB4B Products

Product Documents for EFCAB4B Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EFCAB4B Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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