eIF2B1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-57644

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all eIF2B1 Antibodies »

Product Summary for eIF2B1 Antibody

Immunogen

Synthetic peptides corresponding to EIF2B1(eukaryotic translation initiation factor 2B, subunit 1 alpha) The peptide sequence was selected from the C terminal of EIF2B1. Peptide sequence ADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKL. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for eIF2B1 Antibody

Western Blot: eIF2B1 Antibody [NBP1-57644]

Western Blot: eIF2B1 Antibody [NBP1-57644]

Western Blot: eIF2B1 Antibody [NBP1-57644] - Jurkat cell lysate, concentration 0.2-1 ug/ml.
Immunohistochemistry: eIF2B1 Antibody [NBP1-57644]

Immunohistochemistry: eIF2B1 Antibody [NBP1-57644]

Immunohistochemistry: eIF2B1 Antibody [NBP1-57644] - Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: N/A Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec

Applications for eIF2B1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: eIF2B1

EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM).

Alternate Names

EIF2B, EIF-2B, eIF-2B GDP-GTP exchange factor subunit alpha, EIF-2Balpha, EIF2BAMGC117409, eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD), eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa, MGC125868, MGC125869, translation initiation factor eIF-2B subunit alpha

Gene Symbol

EIF2B1

UniProt

Q14232 (Human)

Additional eIF2B1 Products

Product Documents for eIF2B1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for eIF2B1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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