ELAC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12934

Novus Biologicals, part of Bio-Techne
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NBP3-12934
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Chimpanzee (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ELAC2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ELAC2. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for ELAC2 Antibody

Western Blot: ELAC2 Antibody [NBP3-12934]

Western Blot: ELAC2 Antibody [NBP3-12934]

Western Blot: ELAC2 Antibody [NBP3-12934] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with ELAC2 antibody (NBP3-12934) diluted at 1:1000.
Immunohistochemistry-Paraffin: ELAC2 Antibody [NBP3-12934]

Immunohistochemistry-Paraffin: ELAC2 Antibody [NBP3-12934]

Immunohistochemistry-Paraffin: ELAC2 Antibody [NBP3-12934] - ELAC2 antibody detects ELAC2 protein at cytoplasm and nucleus in human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. ELAC2 antibody (NBP3-12934) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Immunoprecipitation: ELAC2 Antibody [NBP3-12934]

Immunoprecipitation: ELAC2 Antibody [NBP3-12934]

Immunoprecipitation: ELAC2 Antibody [NBP3-12934] - Immunoprecipitation of ELAC2 protein from Jurkat whole cell extracts using 5 ug of ELAC2 antibody (NBP3-12934). Western blot analysis was performed using ELAC2 antibody (NBP3-12934). EasyBlot anti-Rabbit IgG was used as a secondary reagent.

Applications for ELAC2 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ELAC2

The protein encoded by the ELAC2 gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity,which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activatedSmad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expressioncan suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased riskof prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. (providedby RefSeq)

Alternate Names

EC 3.1.26.11, elaC homolog 2 (E. coli), ElaC homolog protein 2, ELC2, FLJ10530, FLJ36693, FLJ42848, Heredity prostate cancer protein 2, HPC2elaC (E. coli) homolog 2, putative prostate cancer susceptibility protein HPC2/ELAC2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z (long form), tRNase Z 2, zinc phosphodiesterase ELAC protein 2

Gene Symbol

ELAC2

Additional ELAC2 Products

Product Documents for ELAC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ELAC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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