Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Emerin Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Emerin. The immunogen is located within the first 50 amino acids of Emerin. Amino Acid Squence: STRRLYEKKIFEYETQRRR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Emerin Antibody - BSA Free

Western Blot: Emerin AntibodyBSA Free [NBP1-76757]

Western Blot: Emerin AntibodyBSA Free [NBP1-76757]

Western Blot: Emerin Antibody [NBP1-76757] - Human skeletal muscle tissue lysate with Emerin antibody at (A) 0.5 and (B) 1 ug/ml.
Emerin Antibody - BSA Free

Immunohistochemistry: Emerin Antibody - BSA Free [NBP1-76757] -

Immunohistochemistry: Emerin Antibody - BSA Free [NBP1-76757] - Immunohistochemistry of emerin in human skeletal muscle tissue with emerin antibody at 2.5 u/mL.
Emerin Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Emerin Antibody - BSA Free [NBP1-76757] -

Immunocytochemistry/ Immunofluorescence: Emerin Antibody - BSA Free [NBP1-76757] - Immunofluorescence of Emerin in Human Skeletal Muscle cells with Emerin antibody at 5 ug/mL.

Applications for Emerin Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Emerin

Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family that includes proteins such as LAP2 and MAN1. Each family member, including Emerin, has an ~40 amino acid LEM-domains that binds barrier-to-autointegration (BANF1), a conserved chromatin protein that also serves as a host cell component of retroviral integration complexes, including that of HIV. Emerin is anchored at the inner membrane of the nuclear envelope where it binds to nuclear intermediate filaments that are formed by lamin proteins. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.

Alternate Names

emerin, Emery-Dreifuss muscular dystrophy, LEM domain containing 5, STAEDMDLEMD5

Gene Symbol

EMD

UniProt

NP_000108 (Human)

Additional Emerin Products

Product Documents for Emerin Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Emerin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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