EMMPRIN/CD147 Antibody (JF1-045)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-66820

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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NBP2-66820
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # JF1-045

Concentration

1 mg/ml

View all EMMPRIN/CD147 Antibodies »

Product Specifications

Immunogen

Synthetic peptide within Human EMMPRIN/CD147 aa 171-204 / 385. (SwissProt: P35613 Human; SwissProt: P18572 Mouse; SwissProt: P26453 Rat)

Localization

Cell membrane, Melanosome.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for EMMPRIN/CD147 Antibody (JF1-045)

Immunocytochemistry/ Immunofluorescence: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820]

Immunocytochemistry/ Immunofluorescence: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820]

Immunocytochemistry/Immunofluorescence: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820] - Staining CD147 in SKOV-3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X-100/PBS.
Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820]

Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820]

Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820] - Analysis of paraffin-embedded rat brain tissue using anti-CD147 antibody. Counter stained with hematoxylin.
Immunocytochemistry/ Immunofluorescence: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820]

Immunocytochemistry/ Immunofluorescence: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820]

Immunocytochemistry/Immunofluorescence: EMMPRIN/CD147 Antibody (JF1-045) [NBP2-66820] - Staining CD147 in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X-100/PBS.
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Applications for EMMPRIN/CD147 Antibody (JF1-045)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:5,000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 4 using NBP2-66820 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

TBS (pH7.4), 0.05% BSA, 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EMMPRIN/CD147

CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.

Long Name

Extracellular Matrix Metalloproteinase Inducer

Alternate Names

Basigin, BSG, CD147

Gene Symbol

BSG

Additional EMMPRIN/CD147 Products

Product Documents for EMMPRIN/CD147 Antibody (JF1-045)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for EMMPRIN/CD147 Antibody (JF1-045)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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