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EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80717

Novus Biologicals, part of Bio-Techne
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NBP2-80717
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Key Product Details

Species Reactivity

Rat

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OX-47

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

T blasts from a mixed lymphocyte reaction.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free

Immunohistochemistry: EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free [NBP2-80717]

Immunohistochemistry: EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free [NBP2-80717]

Immunohistochemistry: EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free [NBP2-80717] - Analysis of FFPE tissue section of rat kidney using 1:100 dilution of CD147 antibody (clone OX-47). The staining was detected using HRP-labelled secondary antibody and DAB reagent which followed counterstaining of sections with hematoxylin. This antibody
Flow Cytometry: EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free [NBP2-80717]

Flow Cytometry: EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free [NBP2-80717]

Flow Cytometry: EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free [NBP2-80717] - Rat Splenocytes were stained with EMMPRIN/CD147 (OX-47) antibody NB100-64848 (blue) and a matched isotype control NBP2-27287 (orange). Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at room temperature. The antibodies were directly conjugated to Alexa Fluor 488.

Applications for EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1 ug/ml

Immunocytochemistry/ Immunofluorescence

1:10 - 1:500

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Frozen

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100 - 1:500

Western Blot

1:100 - 1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EMMPRIN/CD147

CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.

Long Name

Extracellular Matrix Metalloproteinase Inducer

Alternate Names

Basigin, BSG, CD147

Gene Symbol

BSG

Additional EMMPRIN/CD147 Products

Product Documents for EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for EMMPRIN/CD147 Antibody (OX-47) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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