EMMPRIN/CD147 Antibody (S04-5B3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20062

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20062-100ul
NBP3-20062-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S04-5B3

Concentration

0.3 mg/ml

View all EMMPRIN/CD147 Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human EMMPRIN/CD147 (Uniprot # P35613)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for EMMPRIN/CD147 Antibody (S04-5B3)

Western Blot: EMMPRIN/CD147 Antibody (S04-5B3) [NBP3-20062]

Western Blot: EMMPRIN/CD147 Antibody (S04-5B3) [NBP3-20062]

Western Blot: EMMPRIN/CD147 Antibody (S04-5B3) [NBP3-20062] - Western blot detection of EMMPRIN/CD147 in Hela (Lane 1), Ramos (Lane 2) cell lysates using NBP3-20062 (1:1000 diluted). Predicted band size: 42kDa. Observed band size: 42kDa.
Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (S04-5B3) [NBP3-20062]

Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (S04-5B3) [NBP3-20062]

Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (S04-5B3) [NBP3-20062] - Immunohistochemistry of EMMPRIN/CD147 in paraffin-embedded Human colon cancer tissue using NBP3-20062 at dilution 1/50

Applications for EMMPRIN/CD147 Antibody (S04-5B3)

Application
Recommended Usage

Immunohistochemistry

1/50-1/200

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EMMPRIN/CD147

CD147 plays a pivotal role in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. CD147 also seems to be a receptor for oligomannosidic glycans. In vitro, it promotes outgrowth of astrocytic processes. CD147 forms homooligomers in a cis-dependent manner on the plasma membrane. It forms a complex with MMP1 at the tumor cell surface. CD147 interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. CD147 also interacts with ATP1B2, MAG and L1CAM.

Long Name

Extracellular Matrix Metalloproteinase Inducer

Alternate Names

Basigin, BSG, CD147

Gene Symbol

BSG

Additional EMMPRIN/CD147 Products

Product Documents for EMMPRIN/CD147 Antibody (S04-5B3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for EMMPRIN/CD147 Antibody (S04-5B3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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