EMR3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14560

Novus Biologicals, part of Bio-Techne
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NBP3-14560
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all EMR3 Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from N-Terminus extracellular domain of human EMR3.

Epitope

N-Terminus

Reactivity Notes

Expected reactivity based on percent sequence identity: Gorilla (89%), Marmoset (83%)

Specificity

Human EMR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for EMR3 Antibody

Immunohistochemistry-Paraffin: EMR3 Antibody [NBP3-14560]

Immunohistochemistry-Paraffin: EMR3 Antibody [NBP3-14560]

Immunohistochemistry-Paraffin: EMR3 Antibody [NBP3-14560] - Immunohistochemistry of formalin-fixed, paraffin-embedded human tissue staining macrophage after heat-induced antigen retrieval.

Applications for EMR3 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: EMR3

EMR3 is an Orphan-B GPCR with an unknown ligand. Two variants are produced by alternative splicing. One form encodes a 652-amino acid GPCR consisting of two EGF-like domains and a mucin stalk, while the other is a truncated soluble form containing only two EGF-like domains. EMR3 and EMR2 share a high degree of sequence identity in the transmembrane domains. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.

Long Name

EGF-like Module Containing, Mucin-like, Hormone Receptor-like 3

Alternate Names

egf-like module containing, mucin-like, hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3, egf-like module-containing mucin-like receptor 3

Gene Symbol

ADGRE3

Additional EMR3 Products

Product Documents for EMR3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for EMR3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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