EMSY Antibody (5D1)

Novus Biologicals, part of Bio-Techne | Catalog # H00056946-M01

Novus Biologicals, part of Bio-Techne
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H00056946-M01
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG3 Kappa Clone # 5D1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all EMSY Antibodies »

Product Specifications

Immunogen

C11orf30 (NP_064578, 1081 a.a. ~ 1178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PASSEKQTASQVEQPIITQGSSVTKITFEGRQPPTVTKITGGSSVPKLTSPVTSISPIQASEKTAVSDILKMSLMEAQIDTNVEHMIVDPPKKALATS

Reactivity Notes

Human. Other species not tested.

Specificity

C11orf30 - chromosome 11 open reading frame 30

Clonality

Monoclonal

Host

Mouse

Isotype

IgG3 Kappa

Scientific Data Images for EMSY Antibody (5D1)

Immunocytochemistry/ Immunofluorescence: EMSY Antibody (5D1) [H00056946-M01]

Immunocytochemistry/ Immunofluorescence: EMSY Antibody (5D1) [H00056946-M01]

Immunocytochemistry/Immunofluorescence: EMSY Antibody (5D1) [H00056946-M01] - Analysis of monoclonal antibody to C11orf30 on HeLa cell . Antibody concentration 10 ug/ml.

Applications for EMSY Antibody (5D1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: EMSY

EMSY is a novel protein whose sequence is found in a chromosomal region known to be involved in breast and ovarian cancer (1). The N-terminus of EMSY binds BRCA2 (exon 3). EMSY is capable of silencing the exon 3 encoded transcrip-tional activation domain of BRCA2. EMSY, just like BRCA2, is located in the nucleus and functions with DNA repair and transcriptional regulation factors (2). EMSY was found to be overactive in 13% of sporadic cases of breast cancer and 17% of ovarian cancers and it was also linked with poor survival, specifically in node-negative breast cancer, suggesting that it may be of prognostic value (1).

Alternate Names

chromosome 11 open reading frame 30, EMSYFLJ90741, protein EMSY

Entrez Gene IDs

56946 (Human)

Gene Symbol

EMSY

OMIM

608573 (Human)

UniProt

NP_064578 (Human)

Additional EMSY Products

Product Documents for EMSY Antibody (5D1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for EMSY Antibody (5D1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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