EphA4 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB110-39007

Novus Biologicals, part of Bio-Techne
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NB110-39007
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Key Product Details

Species Reactivity

Validated:

Human, Monkey, Primate

Predicted:

Canine (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all EphA4 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from internal region of human EphA4.

Epitope

internal domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Bovine (88%), Bat (88%), Hamster (88%), Porcine (88%), Opossum (88%), Turkey (88%), Chicken (88%), Mouse (81%), Rat (81%), Rabbit (81%), Xenopus (81%).

Specificity

Human EPHA4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for EphA4 Antibody - BSA Free

Immunohistochemistry-Paraffin: EphA4 Antibody - BSA Free [NB110-39007]

Immunohistochemistry-Paraffin: EphA4 Antibody - BSA Free [NB110-39007]

Immunohistochemistry-Paraffin: EphA4 Antibody - BSA Free [NB110-39007] - Analysis of anti-EPHA4 antibody with human glomerulus at concentration 6 ug/ml.

Applications for EphA4 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

6 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: EphA4

Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5 but binds more poorly to ephrin-A2 and -A3. Eph receptor A4 may play a role in a signal transduction process involved in hindbrain pattern formation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death.

Long Name

Eph Receptor A4

Alternate Names

Cek8, Hek8, Sek1, Tyro1

Entrez Gene IDs

2043 (Human)

Gene Symbol

EPHA4

Additional EphA4 Products

Product Documents for EphA4 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for EphA4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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