EphB1 Antibody (022)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90032

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-90032-100ul
NBP2-90032-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 022

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all EphB1 Antibodies »

Product Summary for EphB1 Antibody (022)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human EphB1 (Uniprot#: P54762-1; Met1-Pro540).

Specificity

No cross-reactivity in ELISA with: Human EPHB4Human EPHB6Mouse EphA1Mouse EphA4Mouse EphA6Mouse EphA7Mouse EphB3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for EphB1 Antibody (022)

Application
Recommended Usage

ELISA

1:5000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: EphB1

EphrinB proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. EphrinB molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing EphrinB on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of EphrinB is thought to be a critical component of this reverse signaling event. Recent work suggests that phosphorylation of a specific EphrinB residue (Tyr298) plays a key role in EphrinB signaling. (3, 5)

Long Name

Eph Receptor B1

Alternate Names

Cek6, Elk, Hek6, Net

Gene Symbol

EPHB1

Additional EphB1 Products

Product Documents for EphB1 Antibody (022)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for EphB1 Antibody (022)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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