ERAS Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-79602

Novus Biologicals, part of Bio-Techne
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NBP1-79602
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all ERAS Antibodies »

Product Summary for ERAS Antibody

Immunogen

Synthetic peptide directed towards the N terminal of human ErasThe immunogen for this antibody is Eras. Peptide sequence LPTKSSILDLSSGTPCTRSPEESHEAWAQCKDAGRQLPEYKAVVVGASGV. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for ERAS Antibody

Western Blot: ERAS Antibody [NBP1-79602]

Western Blot: ERAS Antibody [NBP1-79602]

Western Blot: ERAS Antibody [NBP1-79602] - Mouse Heart Lysate 1ug/ml Gel Concentration 12%

Applications for ERAS Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ERAS

ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.

Alternate Names

Embryonic stem cell-expressed Ras, E-Ras, ES cell expressed Ras, HRAS2MGC126693, HRASPGTPase ERas, MGC126691, small GTPase protein E-Ras, v-Ha-ras Harvey rat sarcoma viral oncogene homolog 2, v-Ha-ras Harvey rat sarcoma viral oncogene homolog pseudogene

Gene Symbol

ERAS

UniProt

NP_853526 (Mouse)

Additional ERAS Products

Product Documents for ERAS Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ERAS Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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