ErbB4/Her4 Antibody (S07-2H1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15027

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15027-100ul
NBP3-15027-25ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S07-2H1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ErbB4/Her4 Antibodies »

Product Specifications

Immunogen

Recombinant protein of human ErbB4/Her4 (Uniprot#: Q15303)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

180 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ErbB4/Her4 Antibody (S07-2H1)

Western Blot: ErbB4/Her4 Antibody (S07-2H1) [NBP3-15027]

Western Blot: ErbB4/Her4 Antibody (S07-2H1) [NBP3-15027]

Western Blot: ErbB4/Her4 Antibody (S07-2H1) [NBP3-15027] - Western blot detection of ErbB4/Her4 in Hela, A549, HL-60, U2OS, C6 cell lysates using ErbB4/Her4 Rabbit mAb (1:1000 diluted). Predicted band size: 147kDa. Observed band size: 180kDa.

Applications for ErbB4/Her4 Antibody (S07-2H1)

Application
Recommended Usage

Western Blot

1/1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ErbB4/Her4

erbB4/HER4 is a receptor tyrosine kinase that belongs to the human epidermal growth factor receptor (EGFR) family. erbB4/HER4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain, and cerebellum (1). erbB4/HER4 is activated by neuregulins (NRG), betacellulin (BTC), and heparin-binding EGF-like growth factor (2). Neuregulins regulate the expression of ligand- and voltage-gated channels in neurons and skeletal muscle by the activation of ErbB 1-4. The erbB4/HER4 receptor is unique among these receptors because its C-terminal tail binds to a protein motif known as the PDZ domain (3).

Long Name

Receptor Tyrosine Protein Kinase ErbB4

Alternate Names

HER4

Gene Symbol

ERBB4

Additional ErbB4/Her4 Products

Product Documents for ErbB4/Her4 Antibody (S07-2H1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ErbB4/Her4 Antibody (S07-2H1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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