ESX1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13973

Novus Biologicals, part of Bio-Techne
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NBP2-13973
NBP2-13973-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ESX1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: HEPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ESX1 Antibody

Immunohistochemistry-Paraffin: ESX1 Antibody [NBP2-13973]

Immunohistochemistry-Paraffin: ESX1 Antibody [NBP2-13973]

Immunohistochemistry-Paraffin: ESX1 Antibody [NBP2-13973] - Staining in human testis and skeletal muscle tissues using anti-ESX1 antibody. Corresponding ESX1 RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: ESX1 Antibody [NBP2-13973]

Immunocytochemistry/ Immunofluorescence: ESX1 Antibody [NBP2-13973]

Immunocytochemistry/Immunofluorescence: ESX1 Antibody [NBP2-13973] - Staining of human cell line HEK 293 shows localization to nuclear speckles.
Immunohistochemistry-Paraffin: ESX1 Antibody [NBP2-13973]

Immunohistochemistry-Paraffin: ESX1 Antibody [NBP2-13973]

Immunohistochemistry-Paraffin: ESX1 Antibody [NBP2-13973] - Staining of human skeletal muscle shows low expression as expected.
View 1 more images

Applications for ESX1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ESX1

The ESX1 gene encodes a 406 amino acid long, 44kDA homeobox protein ESX1 that functions in cell cycle progression and transcription during spermatogenesis and plays a critical role in placental development. ESX1 interacts with genes EXOC2 and TRAP1 and is linked to diseases such as testicular germ cell tumors, delayed puberty, hypopituitarism, tuberculosis, and holoprosencephaly.

Alternate Names

ESX homeobox 1, ESX1LESX1R, ESX1-related protein, ESXR1homeobox protein ESX1, Extraembryonic, spermatogenesis, homeobox 1, extraembryonic, spermatogenesis, homeobox 1 homolog, extraembryonic, spermatogenesis, homeobox 1 homolog (mouse)

Gene Symbol

ESX1

Additional ESX1 Products

Product Documents for ESX1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ESX1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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