Exosome component 4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82170

Novus Biologicals, part of Bio-Techne
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NBP1-82170
NBP1-82170-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Exosome component 4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FVDGTALADLSHVEEAAGGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVREASILL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Exosome component 4 Antibody

Western Blot: Exosome component 4 Antibody [NBP1-82170]

Western Blot: Exosome component 4 Antibody [NBP1-82170]

Western Blot: Exosome component 4 Antibody [NBP1-82170] - Analysis in control (vector only transfected HEK293T lysate) and EXOSC4 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunocytochemistry/ Immunofluorescence: Exosome component 4 Antibody [NBP1-82170]

Immunocytochemistry/ Immunofluorescence: Exosome component 4 Antibody [NBP1-82170]

Immunocytochemistry/Immunofluorescence: Exosome component 4 Antibody [NBP1-82170] - Staining of human cell line U-251 MG shows localization to cytosol & intermediate filaments. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Exosome component 4 Antibody [NBP1-82170]

Immunohistochemistry-Paraffin: Exosome component 4 Antibody [NBP1-82170]

Immunohistochemistry-Paraffin: Exosome component 4 Antibody [NBP1-82170] - Staining of human testis shows moderate cytoplasmic and nuclear positivity in cells in seminiferous ducts and Leydig cells

Applications for Exosome component 4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Exosome component 4

EXOSC4 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAscontaining AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7Spre-RNA to the mature 5.8S rRNA. Has

Alternate Names

exosome complex exonuclease RRP41, exosome component 4Rrp41p, exosome component Rrp41, FLJ20591, p12ARibosomal RNA-processing protein 41, RRP41A, RRP41Ski6p, SKI6hRrp41p

Gene Symbol

EXOSC4

Additional Exosome component 4 Products

Product Documents for Exosome component 4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Exosome component 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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