Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all Exosome component 5 Antibodies »

Product Specifications

Immunogen

The immunogen this antibody was made to, maps to a region between residue 1 and 50 of human Exosome Component 5 using the numbering given in entry NP_064543.3 (GeneID 56915).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Exosome component 5 Antibody

Western Blot: Exosome component 5 Antibody [NBP2-22241]

Western Blot: Exosome component 5 Antibody [NBP2-22241]

Western Blot: Exosome component 5 Antibody [NBP2-22241] - Whole cell lysate from 293T (15 and 50 ug), HeLa (50 ug), and Jurkat (50 ug) cells. NBP2-22241 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Immunoprecipitation: Exosome component 5 Antibody [NBP2-22241]

Immunoprecipitation: Exosome component 5 Antibody [NBP2-22241]

Immunoprecipitation: Exosome component 5 Antibody [NBP2-22241] - Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: NBP2-22241 used for IP at 6 ug/mg lysate. EXOSC5 was also immunoprecipitated by rabbit anti-EXOSC5 antibody. For blotting immunoprecipitated EXOSC5, NBP2-22241 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for Exosome component 5 Antibody

Application
Recommended Usage

Immunoprecipitation

2 - 10 ug/mg

Western Blot

1:2000 - 1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Exosome component 5

EXOSC5 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAscontaining AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7Spre-RNA to the mature 5.8S rRNA. Has

Alternate Names

CML28, exosome complex exonuclease RRP46, exosome component 5Chronic myelogenous leukemia tumor antigen 28, exosome component Rrp46, hRrp46p, MGC12901, p12BMGC111224, RRP41B, Rrp46p, RRP46Ribosomal RNA-processing protein 46

Gene Symbol

EXOSC5

UniProt

NP_064543.3 (Human)

Additional Exosome component 5 Products

Product Documents for Exosome component 5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Exosome component 5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.