FACA/FANCA Antibody (4Q1Q8)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16818
Recombinant Monoclonal Antibody
Key Product Details
Species Reactivity
Validated:
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # 4Q1Q8
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for FACA/FANCA Antibody (4Q1Q8)
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2-104 of human FACA/FANCA (O15360). SDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASR
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for FACA/FANCA Antibody (4Q1Q8)
![Western Blot: FACA/FANCA Antibody (4Q1Q8) [NBP3-16818]](https://resources.bio-techne.com/images/products/FACA-FANCA-Antibody-4Q1Q8-Western-Blot-NBP3-16818-img0001.jpg "Western Blot: FACA/FANCA Antibody (4Q1Q8) [NBP3-16818]")
Western Blot: FACA/FANCA Antibody (4Q1Q8) [NBP3-16818]
Western Blot: FACA/FANCA Antibody (4Q1Q8) [NBP3-16818] - Western blot analysis of extracts of various cell lines, using FACA/FANCA Rabbit mAb (NBP3-16818) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.Applications for FACA/FANCA Antibody (4Q1Q8)
Application
Recommended Usage
Western Blot
1:500 - 1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at -20C. Avoid freeze-thaw cycles.
Background: FACA/FANCA
Defects in FANCA result in Fanconi Anemia, a genetically heterogeneous autosomal recessive disorder characterized by progressive pancytopenia, diverse congenital malformations, and a predisposition to develop malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair. At the cellular level FANCA defects cause a hypersensitivity to DNA-damaging agents, chromosomal instability, and defective DNA repair.
Long Name
Fanconi Anemia, Complementation Group A
Alternate Names
FAA, FAH, FANCA, FANCH
Gene Symbol
FANCA
Additional FACA/FANCA Products
Product Documents for FACA/FANCA Antibody (4Q1Q8)
Product Specific Notices for FACA/FANCA Antibody (4Q1Q8)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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