FACA/FANCA Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56898
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunocytochemistry/ Immunofluorescence
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Summary for FACA/FANCA Antibody
Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFF
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for FACA/FANCA Antibody
![Immunocytochemistry/ Immunofluorescence: FACA/FANCA Antibody [NBP2-56898]](https://resources.bio-techne.com/images/products/FACA-FANCA-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-56898-img0001.jpg "Immunocytochemistry/ Immunofluorescence: FACA/FANCA Antibody [NBP2-56898]")
Immunocytochemistry/ Immunofluorescence: FACA/FANCA Antibody [NBP2-56898]
Immunocytochemistry/Immunofluorescence: FACA/FANCA Antibody [NBP2-56898] - Staining of human cell line MCF7 shows localization to nucleus. Antibody staining is shown in green.Applications for FACA/FANCA Antibody
Application
Recommended Usage
Immunocytochemistry/ Immunofluorescence
0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: FACA/FANCA
Defects in FANCA result in Fanconi Anemia, a genetically heterogeneous autosomal recessive disorder characterized by progressive pancytopenia, diverse congenital malformations, and a predisposition to develop malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair. At the cellular level FANCA defects cause a hypersensitivity to DNA-damaging agents, chromosomal instability, and defective DNA repair.
Long Name
Fanconi Anemia, Complementation Group A
Alternate Names
FAA, FAH, FANCA, FANCH
Gene Symbol
FANCA
Additional FACA/FANCA Products
Product Documents for FACA/FANCA Antibody
Product Specific Notices for FACA/FANCA Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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