FADS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-60085

Novus Biologicals, part of Bio-Techne
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NBP1-60085
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all FADS1 Antibodies »

Product Summary for FADS1 Antibody

Immunogen

Synthetic peptides corresponding to FADS1(fatty acid desaturase 1) The peptide sequence was selected from the C terminal of FADS1. Peptide sequence FNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLL. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for FADS1 Antibody

Western Blot: FADS1 Antibody [NBP1-60085]

Western Blot: FADS1 Antibody [NBP1-60085]

Western Blot: FADS1 Antibody [NBP1-60085] - Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0 ug/ml
Immunohistochemistry-Paraffin: FADS1 Antibody [NBP1-60085]

Immunohistochemistry-Paraffin: FADS1 Antibody [NBP1-60085]

Immunohistochemistry-Paraffin: FADS1 Antibody [NBP1-60085] - Human Muscle Tissue, Skeletal muscle cells (Indicated with Arrows) 4-8ug/ml.
Western Blot: FADS1 Antibody [NBP1-60085]

Western Blot: FADS1 Antibody [NBP1-60085]

Western Blot: FADS1 Antibody [NBP1-60085] - Titration: 2.5ug/ml Positive Control: K562 cell lysate.

Applications for FADS1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FADS1

FADS1 is a member of the fatty acid desaturase (FADS) family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs.The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

Long Name

Acyl-CoA

Alternate Names

D5D, Delta(5) desaturase, Delta-5 desaturase, FADSD5

Entrez Gene IDs

3992 (Human)

Gene Symbol

FADS1

UniProt

O60427 (Human)

Additional FADS1 Products

Product Documents for FADS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FADS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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