FAIM1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-77331

Novus Biologicals, part of Bio-Techne
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NB100-77331
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all FAIM Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KKYMEDRSKTTN corresponding to internal region according to NP_001028203.1, NP_001028204.1, NP_060617.1.

Epitope

KKYMEDRSKTTN

Specificity

This antibody is expected to recognise all reported isoforms (NP_001028202.1; NP_001028203.1; NP_001028204.1; NP_060617.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for FAIM1 Antibody

Western Blot: FAIM1 Antibody [NB100-77331]

Western Blot: FAIM1 Antibody [NB100-77331]

Western Blot: FAIM1 Antibody [NB100-77331] - Analysis of FAIM1 using NB100-77331 at 0.5ug/ml in Human Lymph Node lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: FAIM1 Antibody [NB100-77331]

Immunohistochemistry-Paraffin: FAIM1 Antibody [NB100-77331]

Immunohistochemistry-Paraffin: FAIM1 Antibody [NB100-77331] - (2.5ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for FAIM1 Antibody

Application
Recommended Usage

Immunohistochemistry

2 - 3 ug/ml

Immunohistochemistry-Paraffin

2 - 3 ug/ml

Peptide ELISA

Detection limit 1:32000

Western Blot

0.5 - 1 ug/ml
Application Notes
WB: Approx. 25 kDa band observed in human lymph node lysates (calculated MW of 24.0 kDa band according to NP_001028202.1). IHC-P: Human placenta shows cytoplasm staining of trophoblasts.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FAIM

FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas-mediated apoptosis of B and non-B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.

Long Name

Fas Apoptotic Inhibitory Molecule 1

Alternate Names

FAIM1, FAIM2, LFG, NMP35

Entrez Gene IDs

55179 (Human); 23873 (Mouse); 140930 (Rat)

Gene Symbol

FAIM

UniProt

NP_001028202.1 (Human)

Additional FAIM Products

Product Documents for FAIM1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FAIM1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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