FAK [p Tyr397] Antibody (SR1077)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21534

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21534-100ul
NBP3-21534-50ul
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1077

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all FAK Antibodies »

Product Summary for FAK [p Tyr397] Antibody (SR1077)

Immunogen

A synthesized peptide derived from human phospho-FAK [Tyr397] (Uniprot #: Q05397)

Modification

p Tyr397

Specificity

Detects endogenous levels of phospho-FAK [Tyr397]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

119 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FAK [p Tyr397] Antibody (SR1077)

Western Blot: FAK [p Tyr 397] Antibody (SR1077) [NBP3-21534] -

Western Blot: FAK [p Tyr 397] Antibody (SR1077) [NBP3-21534] - Western blot analysis using NBP3-21534 in EGF treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Applications for FAK [p Tyr397] Antibody (SR1077)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FAK

FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation. Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness.

Long Name

Focal adhesion kinase 1

Alternate Names

FADK1, PTK2

Gene Symbol

PTK2

Additional FAK Products

Product Documents for FAK [p Tyr397] Antibody (SR1077)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for FAK [p Tyr397] Antibody (SR1077)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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