Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all FANCB Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 820 and 859 of human Fanconi anemia complementation group B using the numbering given in entry NP_001018123.1 (GeneID 2187).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FANCB Antibody

Immunoprecipitation: FANCB Antibody [NBP1-19087]

Immunoprecipitation: FANCB Antibody [NBP1-19087]

Immunoprecipitation: FANCB Antibody [NBP1-19087] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-FANCB antibody used for IP at 10 ug/mg lysate. FANCB was also immunoprecipitated by rabbit anti-FANCB antibody NBP1-19086, which recognizes an upstream epitope.

Applications for FANCB Antibody

Application
Recommended Usage

Immunoprecipitation

10 ug/mg lysate
Application Notes
This antibody is not recommended for Western Blot analysis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: FANCB

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq]

Alternate Names

EC 2.8.1, EC 3.6.3.14, FA2, FAAP90, FAAP95FAB, FACB, Fanconi anemia group B protein, Fanconi anemia, complementation group B, Fanconi anemia-associated polypeptide of 95 kDa, FLJ34064, Protein FACB

Entrez Gene IDs

2187 (Human)

Gene Symbol

FANCB

UniProt

NP_001018123.1 (Human)

Additional FANCB Products

Product Documents for FANCB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FANCB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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