FANCE Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24840

Novus Biologicals, part of Bio-Techne
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NBP3-24840
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all FANCE Antibodies »

Product Summary for FANCE Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein FANCE using the following amino acid sequence: SGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FANCE Antibody

FANCE Antibody Western Blot: FANCE Antibody [NBP3-24840]

Western Blot: FANCE Antibody [NBP3-24840]

Analysis in human cell line RT-4.
FANCE Antibody Immunocytochemistry/Immunofluorescence: FANCE Antibody [NBP3-24840]

Immunocytochemistry/Immunofluorescence: FANCE Antibody [NBP3-24840]

Staining of human cell line THP-1 shows localization to nucleoplasm, mitotic chromosome & centrosome.

Applications for FANCE Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml

Western Blot

0.04-0.4 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FANCE

FANCE (Fanconi anemia, complementation group E) is a protein involved in DNA repair. Defects in FANCE are the cause of Fanconi anemia, a heterogenous autosomal recessive disorder characterized by congenital malformations and a predisposition to cancer. The FANCE gene is one of 13 complementation groups that include FANCA, FANCB, FANCC, FANCD1/BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, and FANCN/PALB2. FANCE has been shown to mediate the interaction between FANCC and FANCD2.

Alternate Names

FACEFAE, Fanconi anemia group E protein, Fanconi anemia, complementation group E, Protein FACE

Gene Symbol

FANCE

Additional FANCE Products

Product Documents for FANCE Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FANCE Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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