Fc epsilon RI beta/MS4A2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00002206-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Fc epsilon RI beta/MS4A2 Antibodies »

Product Specifications

Immunogen

MS4A2 (NP_000130.1, 1 a.a. - 244 a.a.) full-length human protein. MDTESNRRANLALPQEPSSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTEIVVMMLFLTILGLGSAVSLTICGAGEELKGNKVPEDRVYEELNIYSATYSELEDPGEMSPPIDL

Specificity

Reacts with membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Fc epsilon RI beta/MS4A2 Antibody

Western Blot: Fc epsilon RI beta/MS4A2 Antibody [H00002206-D01P]

Western Blot: Fc epsilon RI beta/MS4A2 Antibody [H00002206-D01P]

Western Blot: Fc epsilon RI beta/MS4A2 Antibody [H00002206-D01P] - Analysis of MS4A2 expression in transfected 293T cell line by MS4A2 polyclonal antibody.Lane 1: MS4A2 transfected lysate(26.50 KDa).Lane 2: Non-transfected lysate.

Applications for Fc epsilon RI beta/MS4A2 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Fc epsilon RI beta/MS4A2

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. Alternative splicing results in multiple transcript variants encoding different isoforms.

Long Name

Fc epsilon Receptor I beta

Alternate Names

APY, ATOPY, Fc epsilonRIb, FCER1B, IGEL, IGER, IGHER, MS4A2

Entrez Gene IDs

2206 (Human)

Gene Symbol

MS4A2

UniProt

NP_000130.1 (Human)

Additional Fc epsilon RI beta/MS4A2 Products

Product Documents for Fc epsilon RI beta/MS4A2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Fc epsilon RI beta/MS4A2 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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