Fc gamma RI/CD64 Antibody (1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90403

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-90403-100ul
NBP2-90403-50ul
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Fc gamma RI/CD64 Antibodies »

Product Summary for Fc gamma RI/CD64 Antibody (1)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Fc gamma RI/CD64 extracellular domain (Accession#: NP_034316.1; Met 1-Pro 297).

Specificity

Has cross-reactivity in ELISA with: Human CD64 / FCGR1ANo cross-reactivity in ELISA with: Mouse CD16-2 /FCGR4Mouse FCGR2B / CD32Mouse FCGR3 / CD16Human CD16a / FCGR3AHuman CD16b / FCGR3BHuman CD32a / FCGR2AHuman CD32b / FCGR2B

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Fc gamma RI/CD64 Antibody (1)

Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403]

Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403]

Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403] - Mouse spleen with rabbit monoclonal antibody (1:200). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).
Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403]

Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403]

Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403] - Mouse brain with rabbit monoclonal antibody (1:200). Positive staining was localized to microglia.
Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403]

Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403]

Immunohistochemistry-Paraffin: Fc gamma RI/CD64 Antibody (1) [NBP2-90403] - Mouse liver with rabbit monoclonal antibody (1:200). Positive staining was localized to Kupffer cell.

Applications for Fc gamma RI/CD64 Antibody (1)

Application
Recommended Usage

ELISA

1:5000-1:10000

Immunohistochemistry

1:100-1:500

Immunohistochemistry-Paraffin

1:100-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fc gamma RI/CD64

CD64 is a 72 kD single chain type I glycoprotein also known as Fc gammaRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN- gamma stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).

Long Name

Fc gamma Receptor I

Alternate Names

CD64, CD64a, FCGR1, FcgRI, FcgRIA, FCRI, FcRIA

Gene Symbol

FCGR1A

Additional Fc gamma RI/CD64 Products

Product Documents for Fc gamma RI/CD64 Antibody (1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Fc gamma RI/CD64 Antibody (1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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