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Fc gamma RIIIB/CD16b Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41105

Novus Biologicals, part of Bio-Techne
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NBP3-41105

Key Product Details

Species Reactivity

Human, Porcine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Human Fc gamma RIIIB/CD16b (Uniprot#: O75015; Pro24-Ser203 (Uniprot#: O75015)

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Fc gamma RIIIB/CD16b Antibody

Fc gamma RIIIB/CD16b Antibody

Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody [NBP3-41105] -

Immunohistochemistry-Paraffin: Fc gamma RIIIB/CD16b Antibody [NBP3-41105] - DAB staining on IHC-P; Samples: Human Small intestine Tissue; Primary Ab: 20ug/ml NBP3-41105; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Fc gamma RIIIB/CD16b Antibody

Western Blot: Fc gamma RIIIB/CD16b Antibody [NBP3-41105] -

Western Blot: Fc gamma RIIIB/CD16b Antibody [NBP3-41105] - Sample: Recombinant protein.

Applications for Fc gamma RIIIB/CD16b Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fc gamma RIIIB/CD16b

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Long Name

Fc gamma Receptor III

Alternate Names

CD16b, FCG3, FCGR3B, FcgRIIIB, FcR-10, FCRIIIB, IGFR3

Gene Symbol

FCGR3B

Additional Fc gamma RIIIB/CD16b Products

Product Documents for Fc gamma RIIIB/CD16b Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Fc gamma RIIIB/CD16b Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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