FcgR4/CD16-2 Antibody (012) [DyLight 680]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05890FR

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 012

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all FcgR4/CD16-2 Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FcgR4/CD16-2 (Accession#: NP_653142.2; Met 1-Gln 203).

Reactivity Notes

Has cross-reactivity in ELISA with:

Human CD64 / FCGR1A

No cross-reactivity in ELISA with:

Human CD16a / FCGR3A / FcRIIIa
Human CD16b / FCGR3B / FcRIIIb
Human CD32a / FCGR2A
Human CD32b / FCGR2B
Mouse CD16 / FCGR3

Specificity

Has cross-reactivity in ELISA with: Human CD64 / FCGR1ANo cross-reactivity in ELISA with: Human CD16a / FCGR3A / FcRIIIa Human CD16b / FCGR3B / FcRIIIb Human CD32a / FCGR2A Human CD32b / FCGR2B Mouse CD16 / FCGR3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for FcgR4/CD16-2 Antibody (012) [DyLight 680]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FcgR4/CD16-2

Fcgr4, also known as Fc Receptor-like 3 (Fcrl3) and CD16-2, is a recently described mouse protein that is closely related to human Fc gamma RIIIA (60% amino acid identity) and may be its true ortholog. Similar to other activating receptors, it possesses a charged residue within its transmembrane domain that is necessary for association with an ITAM bearing accessory protein. CD16-2 mRNA expression was observed in peripheral blood leukocytes, spleen, thymus, colon, and intestine.

Long Name

Fc receptor, IgG, low affinity IV

Alternate Names

CD16-2, Fcrl3

Gene Symbol

Fcgr4

Additional FcgR4/CD16-2 Products

Product Documents for FcgR4/CD16-2 Antibody (012) [DyLight 680]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FcgR4/CD16-2 Antibody (012) [DyLight 680]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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