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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 307307

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FCRL5/FCRL3
Gln16-Arg844
Accession # AAI01067

Specificity

Detects human FCRL5/FCRL3 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) FCRL3 is observed and no cross-reactivity with rhFCRL1, 2, or 4 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for FCRL5/FCRL3 Antibody (307307) [DyLight 680]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FCRL5/FCRL3

Fc receptor homologs, also known as IRTA or IFGP (IgSF, FcR, gp42) proteins, are transmembrane proteins with sequence homology to classical Fc receptors. FcRH have from three to nine Ig-like domains in their extracellular region and variable combinations of cytoplasmic immunotyrosine activation or inhibitory motifs (ITAM or ITIM). FcRH function as activating or inhibitory receptors on discrete B cell populations and are involved in lymphocyte development and transformation. No ligands for these proteins have been identified.

Long Name

Fc Receptor-like 5/3

Additional FCRL5/FCRL3 Products

Product Documents for FCRL5/FCRL3 Antibody (307307) [DyLight 680]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FCRL5/FCRL3 Antibody (307307) [DyLight 680]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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